She blinded me with science! |
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Gorjanec
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Uh, tole bom moral pa parkrat prebrat, da si bom lahko približno sliko v glavi ustvaril |
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Gorjanec
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Gorjanec
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http://www.nytimes.com/2014/12/18/science/space/a-picture-captures-planets-waiting-to-be-born.html?_r=0
Edited by Gorjanec - 25.Dec.2014 at 09:32 |
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Jan Ov Plain
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Hudo! EDIT: Edited by Jan Ov Plain - 10.Jan.2015 at 16:34 |
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Occam's razor can leave a scar, but it can remove the cancer so often caused by the poison of liars and imaginers.
Ignorant men raise questions that wise men answered a thousand years ago. |
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sosicizi
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Sicer zelo lepo odkritje, ampak sem mnenja, da je malce preuranjeno govoriti o novem antibiotiku. Predkličničnih študij (na miših) je bilo zaenkrat namreč zelo malo, da o testih na ljudeh sploh ne govorim. Po mehanizmu delovanje je tale teixobactin podoben nekaterim že znanim antibiotikom (vezava na lipid II, ki je prekurzor v biosintezi celične stene bakterij), na katere se je potem rezistenca razvila (vankomicin, lantibiotiki, manopeptimicini, ramoplanin). Srčno upam, da teixobactin ne bo deležen iste usode kasneje... Molekula ima še par drugih problemov, ki lahko malce zaustavijo njen razvoj oziroma vpliv, ki bi ga imela v boju proti rezistenci; izmed teh velja izpostaviti dejstvo, da deluje le na po Gramu pozitivne bakterije. Dandanes so veliko večji problem infekcije, ki jih povzročajo po G- bakterije. Dodatno težavo predstavljajo fizikalno-kemijske lastnosti spojine, ker je strukturna formula takšna, da bo verjetno možna le intravenska aplikacija, saj bo biološka uporabnost zaradi makrociklične in peptidne strukture nizka.
Kolikor sem jaz prebral tale članke, objavljen v Nature, je bolj pomembno odkritje način, kako so prišli do te spojine. Namreč, z nekim čipom so uspeli gojiti bakterije, za katere velja, da jih je težko gojiti v kulturi. Tako izkoriščajo mehanizme bakterijske neribosomalne sinteze peptidov, ki jih nato izolirajo iz medija, kjer bakterije rastejo. Tako je bazen potencialnih novih (in dosedaj povem neznanih) spojin, ki jih bodo uspeli izolirati v prihodnosti ogromen. Pa še ena stvar, ki me moti ob poročanju takšnih stvari: ne gre za edini nov antibiotik v zadnjih 30 letih. Od leta 2000 je na tržišče prišlo 5 protibakterijskih učinkovin z novim mehanizmom delovanja (sem seveda ne spadajo nove generacije cefalosporinov), in sicer linezolid, daptomicin, retapamulin, fidaksomicin in bedakvilin). Je pa dejstvo, da je tudi to premalo v boju proti rezistenci. |
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Jan Ov Plain
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Hvala za prispevek, sosicizi!:) Nekej tretjega, ampak mi je bilo kar luštno.:)
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Occam's razor can leave a scar, but it can remove the cancer so often caused by the poison of liars and imaginers.
Ignorant men raise questions that wise men answered a thousand years ago. |
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Gorjanec
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http://sploid.gizmodo.com/new-amazing-metal-is-so-hydrophobic-it-makes-water-boun-1680799039
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Jan Ov Plain
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Hudo, akwa!:D Tole mi je tud kar zanimivo! Čimprej v čimveč aparatov! |
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Occam's razor can leave a scar, but it can remove the cancer so often caused by the poison of liars and imaginers.
Ignorant men raise questions that wise men answered a thousand years ago. |
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Jan Ov Plain
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Occam's razor can leave a scar, but it can remove the cancer so often caused by the poison of liars and imaginers.
Ignorant men raise questions that wise men answered a thousand years ago. |
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devlin
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Gorjanec
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Solar flair: NASA mission provides mesmerizing images of the sun
http://edition.cnn.com/2015/02/16/tech/nasa-solar-dynamics-observatory/index.html |
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Gorjanec
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ManowaR
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Jan Ov Plain
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Occam's razor can leave a scar, but it can remove the cancer so often caused by the poison of liars and imaginers.
Ignorant men raise questions that wise men answered a thousand years ago. |
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Jan Ov Plain
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Nori časi prihajajo.:) Kakšen bo že job market čez 20,30 let? Kaj kurec bomo ljudje sploh delal? Will Automation Take Our Jobs? Are computers taking our jobs? It is surprisingly hard to say, largely because of a lack of good data Mja, kdo ve.:S Bo štala ziher!
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Occam's razor can leave a scar, but it can remove the cancer so often caused by the poison of liars and imaginers.
Ignorant men raise questions that wise men answered a thousand years ago. |
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Gorjanec
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Romanček Manna se s tem ukvarja, Manna @ Wikipedia. |
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Haderach
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Medtem v znanosti ...
Researchers Find Missing Link Between the Brain and Immune System http://neurosciencenews.com/lymphatic-system-brain-neurobiology-2080/ Čakaj malo ... kater medicinski ukrep pa direktno posega v človekov imunski sistem??? ... ... ah ne ... to zihr nima veze ... |
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Gorjanec
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Haderach
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Tudi jaz ne vidim nič spornega v članku. In ga tudi nisem nikjer interpretiral ... samo razmišljam ... malo širše ...
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Gorjanec
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Gorjanec
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Gorjanec
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http://skepchick.org/2015/08/i-fucking-love-science-ex-admins-speak-out/
Zato se tudi nisem čudil, ko nihče ni nasprotoval Dejziju, ko je v Zeitgeist debati pljuval čez IFLS. Je bilo pač na mestu |
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+1
IFLS in razni dawkins veleumi mi grejo na kurac bolj od giza powerplanta. Edited by mizzi - 18.Aug.2015 at 13:07 |
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Gorjanec
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Strupi pa to ...
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Lif.
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Jan Ov Plain
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http://www.bbc.com/news/technology-34118482
'Robot ethicist,' LOL! Kurec te gleda, baba! Can't stop progress! |
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Occam's razor can leave a scar, but it can remove the cancer so often caused by the poison of liars and imaginers.
Ignorant men raise questions that wise men answered a thousand years ago. |
||
Gorjanec
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http://www.eurekalert.org/pub_releases/2015-10/ciot-cpu102615.php Nova faza metala \m/ |
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Jan Ov Plain
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Fak.:D
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Occam's razor can leave a scar, but it can remove the cancer so often caused by the poison of liars and imaginers.
Ignorant men raise questions that wise men answered a thousand years ago. |
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Gorjanec
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http://english.ahram.org.eg/NewsContent/9/40/161327/Heritage/Ancient-Egypt/Egypts-Minister-of-Antiquities-reveals-to-Ahram-On.aspx
Should be fun Mogoče pa kako vesoljsko trupelce najdejo notri v piramidah |
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Gorjanec
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http://www.southampton.ac.uk/news/2016/02/5d-data-storage-update.page
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Gorjanec
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The 12 Greatest Challenges for Space Explorationhttp://www.wired.com/2016/02/space-is-cold-vast-and-deadly-humans-will-explore-it-anyway/ |
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Gorjanec
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Gorjanec
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Gorjanec
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devlin
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Mrbit je SETI nekaj ujel, mrbit pa je to samo internet oz. prezgodnje veselje. V glavnem kar je predobro, da bi bilo res navadno ni res.
Edited by devlin - 30.Aug.2016 at 11:24 |
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Gorjanec
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Vader69
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ko vidiš naslov....čaki kuga??
This could be the first observational evidence that our early Universe was once a hologramhttp://www.sciencealert.com/this-might-be-the-first-observational-evidence-that-our-early-universe-was-a-hologram in potem še za lahko noč...mal bolj zajeban članek An unexplained 'void' appears to be pushing the Milky Way through the Universe at 2 million km/h |
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Lif.
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Lif.
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Potty Mouth
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...larper
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Potty Mouth
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Dindu science & technology
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...larper
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devlin
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Lisička me nekaj jebe pa nisem dosti g33ka da bi se mi ljubilo ukvarjati s tem, zato bom priobčil kar takole: https://blog.ycombinator.com/leonard-susskind-on-richard-feynman-the-holographic-principle-and-unanswered-questions-in-physics/?fbclid=IwAR27dQK_g48wktbo0thJLJhj_mgrtFIjhew3bwKbKDxQSS2awtduKUPatmg
Edited by devlin - 10.Dec.2018 at 20:35 |
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devlin
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devlin
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